Ki-67 (C22) Antibody-Delta Biolabs

Product Info
Background	Ki-67 is a nuclear protein that is strictly associated with cell proliferation and may be a requirement for maintaining cell proliferation (1,2). Ki-67 is present during all the phases of the cell cycle (G1, S, G2 and M phase) except for the resting stage G0, making it an excellent marker for determining the growth fraction of a population of cells. Ki-67 has also been studied as a prognostic indicator in several malignant neoplasms and correlate to tumor grade and clinical course (1,2). Examples include non-Hodgkins lymphoma, Glioma, soft tissue sarcoma, and breast cancer.
Origin	Ki-67 (C22) is an affinity purified rabbit polyclonal antibody, raised against a peptide mapping to the carboxy terminus of human Ki-67.
Product Details	Each vial contains 0.200 mg/ml of affinity-purified rabbit IgG, Ki-67 (C22), in 1 ml PBS containing 0.1 % sodium azide and 0.2% gelatin.
Competition Studies	A blocking peptide is also available, DB114P, for use in competition studies. Each vial contains 0.100 mg of peptide in 0.5 ml PBS with 0.1% sodium azide and 0.100 mg BSA.
Immunogen	Synthetic peptide mapping to the carboxy terminus of human Ki-67.
Specificity	Ki-67 (C22) DB114 reacts with Ki-67 of human origin.
Use	Recommended for use by Western blotting and immunohistochemistry.
Storage	Store this product at 4� C, do not freeze. The product is stable for one year from the date of shipment.
References	1.) Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol. 2000, 182(3):311-322. 2.) Endl E, Gerdes J. The Ki-67 protein: fascinating forms and an unknown function. Exp Cell Res. 2000 257(2):231-237.